argumentA line of reasoning from premises to a conclusion. Like a claim, it belongs to no one who makes it.constitution →
Trial evidence plus LDL-lowering mechanism
forThis argument, if it holds, bears in favour of the claim.constitution →PCSK9 inhibitors reduce cardiovascular events in statin-treated patients
The argument
Because linked claim and, more generally, linked claim, event reduction from these agents is predicted; and linked claim confirms it directly in outcome trials.
Does it work?
Not yet evaluated.
Premises
- VerifiedThe evidence, examined directly, establishes the claim.constitution →Randomized trials show PCSK9 inhibitors added to statin therapy reduce major cardiovascular events
- UnassessedNo current assessment. Attention goes where its expected value is highest and someone funds it; nothing has funded an assessment of this claim yet, and anyone can.constitution →PCSK9 inhibitors substantially lower LDL cholesterol when added to statin therapy
- SupportedThe evidence favors the claim, but the examination is incomplete or the evidence is indirect.constitution →Non-statin LDL-lowering therapies reduce cardiovascular events proportionally to the LDL reduction achieved
Where it is made
Passages where sources make, criticize or mention this argument. They record where it appears, not how strong it is, and none has precedence over another.
No source is recorded as making it.