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ShowingImportancePrizesTopicCardiovascular medicine
The medical specialty dealing with disorders of the heart and circulatory system, including their prevention, diagnosis, and treatment.
Colchicine reduces cardiovascular events in patients with coronary artery disease
ContestedCredible evidence or argument exists on multiple sides.constitution →empirical · derivedA factual claim that rests on inference from other evidence rather than direct observation.constitution →ColchicineCoronary artery diseaseimportance · majorImportance 0.65, from 0 to 1 · major: real consequence within a domain, actively argued. Higher-importance claims are worth more to assess, so funding reaches them sooner.constitution →
Some interventions that lower LDL cholesterol failed to reduce cardiovascular events
VerifiedThe claim traces to reliable primary sources through a clear chain of evidence.constitution →empirical · derivedA factual claim that rests on inference from other evidence rather than direct observation.constitution →LDL cholesterolAtherosclerotic cardiovascular diseaseimportance · minorImportance 0.40, from 0 to 1 · minor: narrow or largely settled, cheap to get right. Higher-importance claims are worth more to assess, so funding reaches them sooner.constitution →
Elevated LDL cholesterol causes cardiovascular disease
VerifiedThe claim traces to reliable primary sources through a clear chain of evidence.constitution →empirical · derivedA factual claim that rests on inference from other evidence rather than direct observation.constitution →LDL cholesterolAtherosclerotic cardiovascular diseaseimportance · majorImportance 0.80, from 0 to 1 · major: real consequence within a domain, actively argued. Higher-importance claims are worth more to assess, so funding reaches them sooner.constitution →
In the COLCOT trial, low-dose colchicine reduced cardiovascular events after recent myocardial infarction
UnassessedNo current assessment. Attention goes where its expected value is highest and someone funds it; nothing has funded an assessment of this claim yet, and anyone can.constitution →empirical · derivedA factual claim that rests on inference from other evidence rather than direct observation.constitution →ColchicineCOLCOT trialInflammation in atherosclerosisimportance · minorImportance 0.25, from 0 to 1 · minor: narrow or largely settled, cheap to get right. Higher-importance claims are worth more to assess, so funding reaches them sooner.constitution →
Insulin resistance contributes causally to elevated blood pressure
UnassessedNo current assessment. Attention goes where its expected value is highest and someone funds it; nothing has funded an assessment of this claim yet, and anyone can.constitution →empirical · derivedA factual claim that rests on inference from other evidence rather than direct observation.constitution →Insulin resistanceHypertensionimportance · minorImportance 0.30, from 0 to 1 · minor: narrow or largely settled, cheap to get right. Higher-importance claims are worth more to assess, so funding reaches them sooner.constitution →
PCSK9 inhibitors substantially lower LDL cholesterol when added to statin therapy
UnassessedNo current assessment. Attention goes where its expected value is highest and someone funds it; nothing has funded an assessment of this claim yet, and anyone can.constitution →empirical · derivedA factual claim that rests on inference from other evidence rather than direct observation.constitution →PCSK9 inhibitorsLDL cholesterolimportance · settledImportance 0.15, from 0 to 1 · settled: uncontested, so low even when much depends on it. Higher-importance claims are worth more to assess, so funding reaches them sooner.constitution →
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