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The 2018 'Project DEFUSE' grant proposal drafted by EcoHealth Alliance with the Wuhan Institute of Virology for DARPA, describing proposed work on SARS-related coronaviruses, including insertion of proteolytic cleavage sites and humanized-mouse experiments. Covers its described experiments, review, non-funding, and later document releases; not claims about SARS-CoV-2's actual origin.

The DEFUSE proposal described inserting furin cleavage sites into SARS-related coronaviruses

UnassessedNo current assessment. Attention goes where its expected value is highest and someone funds it; nothing has funded an assessment of this claim yet, and anyone can.constitution →empirical · derivedA factual claim that rests on inference from other evidence rather than direct observation.constitution →Furin cleavage site Virologyimportance · notableImportance 0.45, from 0 to 1 · notable: a contested point in a live debate (also the default before judging). Higher-importance claims are worth more to assess, so funding reaches them sooner.constitution →

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