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Comparative codon usage in sarbecoviruses, especially the arginine codons (CGG vs CGT/CGC/CGA/AGA/AGG) in the SARS-CoV-2 furin cleavage site insert and their rarity in related bat sarbecoviruses; used in arguments about the site's natural versus engineered origin. Not the broader presence/absence or function of the cleavage site itself.

The furin cleavage site in SARS-CoV-2 uses an arginine codon (CGG) uncommon in sarbecoviruses

VerifiedThe evidence, examined directly, establishes the claim.constitution →empirical · derivedA factual claim that rests on inference from other evidence rather than direct observation.constitution →Furin cleavage site SARS-CoV-2 originimportance · minorImportance 0.35, from 0 to 1 · minor: narrow or largely settled, cheap to get right. Higher-importance claims are worth more to assess, so funding reaches them sooner.constitution →

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