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Recovery of Deleted Deep Sequencing Data Sheds More Light on the Early Wuhan SARS-CoV-2 Epidemic

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Phylogenetic analysis of these sequences in the context of carefully annotated existing data suggests that the Huanan Seafood Market sequences that are the focus of the joint WHO-China report are not fully representative of the viruses in Wuhan early in the epidemic. Instead, the progenitor of known SARS-CoV-2 sequences likely contained three mutations relative to the market viruses that made it more similar to SARS-CoV-2's bat coronavirus relatives.

The earliest available SARS-CoV-2 genome sequences are a biased, unrepresentative subset of early infectionsSupported

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Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436388/
Archived copy: https://web.archive.org/web/20240309214554/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436388/
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Facts checked: Nov 9, 2026

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