Unwarranted Exclusion of Intermediate Lineage A-B SARS-CoV-2 Genomes Is Inconsistent with the Two-Spillover Hypothesis of the Origin of COVID-19
Steven E. Massey, Adrian Jones, Daoyu Zhang, Yuri Deigin, Steven C. QuayMicrobiology ResearchPublished Mar 22, 2023doi 10.3390/microbiolres14010033Original︎ ↗
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Consequently, we find that the exclusion of many of the intermediate genomes is unfounded, leaving the conclusion of two natural zoonoses unsupported. ... Consequently, confirmation of the existence of an intermediate A-B genome from humans would falsify their hypothesis of two spillovers.
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The two lineages are differentiated by two SNVs; hence, a single-SNV A-B intermediate must have occurred in an unsampled animal host if the two-spillover hypothesis is correct... [the] exclusion of intermediate genomes is unfounded, leaving the conclusion of two natural zoonoses unsupported.
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Record
- Kind
- journal article
- Authors
- Steven E. Massey, Adrian Jones, Daoyu Zhang, Yuri Deigin, Steven C. Quay
- Publisher
- Microbiology Research
- Published
- Mar 22, 2023
- DOI
- 10.3390/microbiolres14010033
- Link
- https://doi.org/10.3390/microbiolres14010033
- Archived copy
- None found
- Stored text
- None; quoted passages only
- Claims extracted
- Not recorded
- Versions
- One known
- Copies
- None recorded
- Corrections
- None recorded
- Facts checked
- Nov 9, 2026
History 3
- Nov 9, 2026FactsFacts fetcher · Facts looked up
- Nov 7, 2026Entered the graphEntered the graph; no copy stored
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